…of things and about the plant side of things, how these unique alkaloids are produced by the plant. Great. And Chris? Hi, I'm Chris McCurdy. I'm a professor of medicinal chemistry and director of the University of Florida's Translational Drug Development…

…It's glad to be back. Hello there. My name is Oliver Grunman. I'm a clinical professor in the same department as Chris, Department of Medicinal Chemistry. Although I'm located out of state in Arizona, I'm primarily involved in Kratom from the perspective of…

…over again now in at least four different surveys that followed subsequently that the benefits are definitely also supporting what Chris and others found in preclinical studies, that it benefits, it may be providing benefits in opioid use disorders, in…

…of folks just for its energetic and its mood elevating properties. And I think that combined with just a really like Chris said, a very well-established grassroots movement has really positioned Kratom uniquely within that space. And the only thing I can, I…

…or extracts of those leaves. And that indicates to me that it might be an indication that it's really the full plant as Chris already pointed out that people are not after just one particular compound in it and just one compound will not give them the…

…into all of these targets now to see. That's really interesting. Sorry, so one thing to point out here is that what Chris just described is basically the pharmacology of individual alkaloids. And then when you look at what kind of products or variety of…

…that user most times has no understanding of what is in that product when they're purchasing it. And so not only, as Chris said earlier, do you have a variability in human makeup and the metabolic processes after consumption, but even your starting point…

…Pharmacy colleagues, and I'm in the College of Ag. So this allows me to have a great conversation with Oliver and Chris and say, okay, if these are attributes that are beneficial, let's move these forward through precision breeding programs to develop new…

…area of ours in trying to understand, is it being produced from certain techniques or certain reactions that are occurring post-harvest? And Chris, you might want to add more to that than just that. I know that's also an area of interest that we share.…

…we're seeing used on a regular basis in the Western hemisphere. And then link that together with what you mentioned earlier, Chris, about poison control center calls. In almost none of these instances did we actually know what was the Kratom product that…

…or for different self-treatments. And pulling that further apart is currently something that we are all very much interested in. Chris and I with other collaborators are working on that from both a survey approach and also from direct questionnaire…

…podcast and I know that guy so I immediately listened to the two episodes and there were maybe more I listened to two with Chris when Chris was alive yeah then I also watched the film being Charlie have you watched it yet Oh man, okay. And you hadn't…

…I know that guy so I immediately listened to the two episodes and there were maybe more I listened to two with Chris when Chris was alive yeah then I also watched the film being Charlie have you watched it yet Oh man, okay. And you hadn't watched it…

…got a hands-off approach to these. Normally I don't. You don't? With Being Charlie, because I listened, I re-listened to the episode with Chris and I think I had said, with Chris and Nick, and I had said to Chris we should watch Being Charlie and he…

…I don't. You don't? With Being Charlie, because I listened, I re-listened to the episode with Chris and I think I had said, with Chris and Nick, and I had said to Chris we should watch Being Charlie and he didn't want to so we didn't watch it and…

…because I listened, I re-listened to the episode with Chris and I think I had said, with Chris and Nick, and I had said to Chris we should watch Being Charlie and he didn't want to so we didn't watch it and then I never circled back to watch it. I…